Reserpine and cerebral vasospasm.

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Reserpine and cerebral vasospasm.

Cerebral vasospasm was produced in the dog basilar artery by topically applied five-day-old clotted autologous blood, but not by freshly drawn blood. The spasm was reversed by methysergide, an antiserotonin agent. However, vasospasm was not produced by five-day-old clotted autologous blood from dogs pretreated with reserpine. This suggests platelet serotonin or a similar, unidentified substance...

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ژورنال

عنوان ژورنال: Stroke

سال: 1977

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.8.1.112